Preparation and evaluation of anti-arthritic activity of Moringa oleifera leaves extract loaded silver nanoparticles
1 Department of Pharmaceutics, Dhanalakshmi Srinivasan College of Pharmacy, Perambalur, Tamil Nadu, India.
2 Student, Dhanalakshmi Srinivasan College of Pharmacy, Perambalur, Tamil Nadu, India.
Research Article
International Journal of Scholarly Research and Reviews, 2023, 02(02), 096–106.
Article DOI: 10.56781/ijsrr.2023.2.2.0023
Publication history:
Received on 24 February 2023; revised on 06 April 2023; accepted on 08 April 2023
Abstract:
Silver Nanoparticles (Ag-NPs) are increasingly used in various fields including medical, food, healthcare consumer and industrial purposes due to their unique physical and chemical properties. The conventional physical and chemical methods of synthesis of Ag-NPs seem to be very expensive and hazardous. Interestingly, biologically prepared Ag-NPs show high yield, solubility and high stability. The biologically Ag-NPs was characterized by UV-visible spectroscopy and SEM with EDAX. The appearance of specific absorbance peak at 440 nm indicates the presence of Ag-NPs. The development of Ag-NPs as anti-arthritic molecules is one of the most interesting approaches for arthritic treatment as it can overcome poor delivery and the problem of drug resistance. The anti-arthritic activity of developed MO-AgNPs was determined by albumin denaturation assay. MO-AgNPs (Moringa Olifera leaves extract loaded silver nanoparticles) exhibit 25% higher anti-arthritic activity when compared with standard Aspirin drug.
Keywords:
Silver Nanoparticles; Moringa Oleifera; Rheumatoid arthritis; Anti-arthritic activity
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0