In silico characterization of three hypothetical proteins in the Monkeypox virus
1 Department of Zoology, Willingdon College, Sangli, India.
2 Department of Zoology, Miraj College, Miraj, India.
3 Department of zoology (research Guide) JJT University, Rajasthan, India.
Research Article
International Journal of Scholarly Research in Science and Technology, 2023, 03(01), 001–007.
Article DOI: 10.56781/ijsrst.2023.3.1.0034
Publication history:
Received on 28 May 2023; revised on 06 July 2023; accepted on 09 July 2023
Abstract:
Monkeypox virus infection and death toll are alarmingly increasing the world over. An effective treatment and control protocol is essential to fight this viral infection. In this, in silico research article, we analyzed three hypothetical protein sequences from the Monkeypox virus. We studied various parameters of these proteins including amino acid composition, instability index, isoelectric point, extinction coefficient, aliphatic index, GRAVY, etc. We also performed MSA to get a clear idea of the mutation and its type and the virus's role over time. We find out various domains and their function that permit the virus during its infection processes. The amphipathicity is validated well. This study will help scientists to develop effective drugs against this virus.
Keywords:
Viral infection; Monkeypox; MSA; Amphipathicity; GRAVY; EC; II
Full text article in PDF:
Copyright information:
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0